Article
Identification of single nucleotide polymorphisms associated with hyperproduction of alpha-toxin in Staphylococcus aureus.
PloS one - 8 Apr 2011
Liang Xudong, Hall Jeffrey W, Yang Junshu, Yan Meiying, Doll Katherine, Bey Russell, Ji Yinduo
Abstract excerpt
The virulence factor α-toxin (hla) is needed by Staphylococcus aureus in order to cause infections in both animals and humans. Although the complicated regulation of hla expression has been well studied in human S. aureus isolates, the mechanisms of of hla regulation in bovine S. aureus isolates remain undefined. In this study, we found that many bovine S. aureus isolates, including the RF122 strain, generate...
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