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Article

Cytomegalovirus drives Vδ2neg γδ T cell inflation in many healthy virus carriers with increasing age.

Clinical and experimental immunology - 1 Jun 2014

Alejenef A, Pachnio A, Halawi M, Christmas S E, Moss P A H, Khan N

Abstract excerpt

Cytomegalovirus (CMV) usually causes lifelong asymptomatic infection, but over time can distort immune profiles. Recent reports describe selective expansion of Vδ2(neg) γδ T cells in healthy and immunocompromised CMV carriers. Having shown previously that virus-specific CD8(+) and CD4(+) T cell responses are increased significantly in elderly CMV carriers, probably driven by chronic stimulation, we hypothesized...

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Source

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Identifiers

PMID: 24547915
DOI: 10.1111/cei.12297
PMCID: PMC4008987

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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