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Article

Neutron structure of the cyclic glucose-bound xylose isomerase E186Q mutant.

Acta crystallographica. Section D, Biological crystallography - 1 Feb 2014

Munshi Parthapratim, Snell Edward H, van der Woerd Mark J, Judge Russell A, Myles Dean A A, Ren Zhong, Meilleur Flora

Abstract excerpt

Ketol-isomerases catalyze the reversible isomerization between aldoses and ketoses. D-Xylose isomerase carries out the first reaction in the catabolism of D-xylose, but is also able to convert D-glucose to D-fructose. The first step of the reaction is an enzyme-catalyzed ring opening of the cyclic substrate. The active-site amino-acid acid/base pair involved in ring opening has long been investigated and several...

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PMID: 24531475
DOI: 10.1107/S1399004713029684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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