Article
The structure of a cold-adapted family 8 xylanase at 1.3 A resolution. Structural adaptations to cold and investgation of the active site.
The Journal of biological chemistry - 28 Feb 2003
Van Petegem Filip, Collins Tony, Meuwis Marie-Alice, Gerday Charles, Feller Georges, Van Beeumen Jozef
Abstract excerpt
Enzymes from psychrophilic organisms differ from their mesophilic counterparts in having a lower thermostability and a higher specific activity at low and moderate temperatures. The current consensus is that they have an increased flexibility, enhancing accommodation and transformation of the substrates at low energy costs. Here we describe the structure of the xylanase from the Antarctic bacterium...
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