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Article

Hypomethylation of the LH/choriogonadotropin receptor promoter region is a potential mechanism underlying susceptibility to polycystic ovary syndrome.

Endocrinology - 1 Apr 2014

Wang Peng, Zhao Han, Li Tao, Zhang Wei, Wu Keliang, Li Mei, Bian Yuehong, Liu Hongbin, Ning Yunna, Li Guangyu, Chen Zi-Jiang

Abstract excerpt

Our previous genome-wide association study identified LH/choriogonadotropin receptor (LHCGR) as a susceptibility gene for polycystic ovary syndrome (PCOS). The objective of this study was to determine whether the genetic or epigenetic components associated with LHCGR participate in the pathogenesis of PCOS. The exons and flanking regions of LHCGR were sequenced from 192 women with PCOS, and no novel somatic...

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Source

Identifiers

PMID: 24527662
DOI: 10.1210/en.2013-1764

Genes

LHCGR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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