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Article

Aberrant expression and DNA methylation of lipid metabolism genes in PCOS: a new insight into its pathogenesis.

Clinical epigenetics - 1 Jan 2018

Pan Jie-Xue, Tan Ya-Jing, Wang Fang-Fang, Hou Ning-Ning, Xiang Yu-Qian, Zhang Jun-Yu, Liu Ye, Qu Fan, Meng Qing, Xu Jian, Sheng Jian-Zhong, Huang He-Feng

Abstract excerpt

Background: Polycystic ovary syndrome (PCOS), whose etiology remains uncertain, is a highly heterogenous and genetically complex endocrine disorder. The aim of this study was to identify differentially expressed genes (DEGs) in granulosa cells (GCs) from PCOS patients and make epigenetic insights into the pathogenesis of PCOS. Results: Included in this study were 110 women with PCOS and 119 women with normal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29344314
DOI: 10.1186/s13148-018-0442-y
PMCID: PMC5767000

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