Article
Association between VEGF-A and VEGFR-2 polymorphisms and response to treatment of neovascular AMD with anti-VEGF agents: a meta-analysis.
The British journal of ophthalmology - 1 Jul 2017
Wu Mingxing, Xiong Haibo, Xu Yan, Xiong Xiaojing, Zou Hongmi, Zheng Minming, Wang Xiuqing, Zhou Xiyuan
Abstract excerpt
AIMS: The purpose of this study is to investigate whether gene polymorphisms of the vascular endothelial growth factor A (VEGF-A) and its receptor (VEGFR-2) have a pharmacogenetics effect on the anti-VEGF treatment for neovascular age-related macular degeneration (nAMD). METHODS: We carried out a...
Topics
- Angiogenesis Inhibitors
- Humans
- Polymorphism, Single Nucleotide
- Vascular Endothelial Growth Factor A
- Vascular Endothelial Growth Factor Receptor-2
- Wet Macular Degeneration