Article
VEGF-A polymorphisms predict short-term functional response to intravitreal ranibizumab in exudative age-related macular degeneration.
Pharmacogenomics - 1 Apr 2013
Lazzeri Stefano, Figus Michele, Orlandi Paola, Fioravanti Anna, Di Desidero Teresa, Agosta Elisa, Sartini Maria Sole, Posarelli Chiara, Nardi Marco, Danesi Romano, Bocci Guido
Abstract excerpt
AIM: To investigate the association between VEGF gene SNPs and early response to intravitreal ranibizumab for exudative age-related macular degeneration. MATERIALS & METHODS: Sixty-four patients (64 eyes) were prospectively enrolled and treated for neovascular age-related macular degeneration with ranibizumab monotherapy. Visual acuity was measured using the ETDRS chart. A loading phase of 3 monthly intravitreal...
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