Article
Mutations of MC4R gene and its association with economic traits in Qinchuan cattle.
Molecular biology reports - 1 Jan 2010
Liu Hongyu, Tian Wanqiang, Zan Linsen, Wang Hongbo, Cui Huan
Abstract excerpt
MC4R belongs to a seven-transmembrane G-protein-coupled receptor which may regulate body composition and insulin action. Many mutations in the MC4R gene are associated with obesity, energy expenditure and serum triglyceride levels in human and animals. Six mutations in the MC4R gene were identified in our study (-293C>G, -193A>T, -192T>G, -129A>G, -84T>C and 1,069C>G). The -129A>G was significantly associated...
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