Article
Association between P478S polymorphism of the filaggrin gene & atopic dermatitis.
The Indian journal of medical research - 1 Dec 2013
Kim Seon-Young, Yang Sung Wan, Kim Hye-Lin, Kim Sung-Hoon, Kim Seong Joon, Park Sun-Min, Son Musong, Ryu Sahyun, Pyo Young-Seok, Lee Jae-Seok, Kim Kyu Seok, Kim Yoon Bum, Hong Seung-Heon, Um Jae-Young
Abstract excerpt
BACKGROUND & OBJECTIVES: Atopic diseases, including atopic dermatitis (AD), allergy and asthma, are complex diseases resulting from the effect of multiple genetic and interacting environmental factors on their pathophysiology. The genetic basis is incompletely understood; however, recent studies have shown an association between loss-of-function variants of the filaggrin gene (FLG) and atopic dermatitis. The aim...
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