Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional Epigenomics Identifies Genes Frequently Silenced in Prostate Cancer

15 May 2005

Abstract excerpt

In many cases, silencing of gene expression by CpG methylation is causally involved in carcinogenesis. Furthermore, cancer-specific CpG methylation may serve as a tumor marker. In order to identify candidate genes for inactivation by CpG methylation in prostate cancer, the prostate cancer cell lines LNCaP, PC3, and Du-145 were treated with 5-aza-2' deoxycytidine and trichostatin A, which leads to reversion of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15899813
DOI: 10.1158/0008-5472.can-04-4407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional Epigenomics Identifies Genes Frequently Silenced in Prostate CancerPMID 15899813Read ↗

PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer.Semantic proximity Read ↗

Deregulation of an imprinted gene network in prostate cancerSemantic proximity Read ↗

Promoter Hypermethylation in Prostate CancerSemantic proximity Read ↗

Methylated genes as potential biomarkers in prostate cancerSemantic proximity Read ↗

In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancerSemantic proximity Read ↗

Identification of Differentially Methylated Genes in Normal Prostate Tissues from African American and Caucasian MenSemantic proximity Read ↗

A DNA hypermethylation profile reveals new potential biomarkers for prostate cancer diagnosis and prognosisSemantic proximity Read ↗

Identification of New Differentially Methylated Genes That Have Potential Functional Consequences in Prostate CancerSemantic proximity Read ↗

KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer.Semantic proximity Read ↗

A new metabolic gene signature in prostate cancer regulated by JMJD3 and EZH2Semantic proximity Read ↗

Genome-Wide Methylation Analysis of Prostate Tissues Reveals Global Methylation Patterns of Prostate CancerSemantic proximity Read ↗

Tazarotene-Induced Gene 1 (TIG1) Expression in Prostate Carcinomas and Its Relationship to TumorigenicitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.