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Article

The serotonin transporter polymorphism rs25531 is associated with irritable bowel syndrome.

Digestive diseases and sciences - 1 Dec 2009

Kohen Ruth, Jarrett Monica E, Cain Kevin C, Jun Sang-Eun, Navaja Grace P, Symonds Sarah, Heitkemper Margaret M

Abstract excerpt

Irritable bowel syndrome is a frequent gastrointestinal disorder of unknown etiology. The serotonin transporter regulates the intensity and duration of serotonin signaling in the gut and is, therefore, an attractive candidate gene for irritable bowel syndrome. Previous studies investigating the 5-HTTLPR and Stin2 VNTR polymorphisms of the serotonin transporter have proved inconclusive. In this exploratory study...

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Identifiers

PMID: 19125330
DOI: 10.1007/s10620-008-0666-3
PMCID: PMC2937164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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