Article
Water-containing hydrogen-bonding network in the active center of channelrhodopsin.
Journal of the American Chemical Society - 5 Mar 2014
Ito Shota, Kato Hideaki E, Taniguchi Reiya, Iwata Tatsuya, Nureki Osamu, Kandori Hideki
Abstract excerpt
Channelrhodopsin (ChR) functions as a light-gated ion channel in Chlamydomonas reinhardtii. Passive transport of cations by ChR is fundamentally different from the active transport by light-driven ion pumps such as archaerhodopsin, bacteriorhodopsin, and halorhodopsin. These microbial rhodopsins are important tools for optogenetics, where ChR is used to activate neurons by light, while the ion pumps are used for...
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