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Article

Polydiacetylene-based high-throughput screen for surfactin producing strains of Bacillus subtilis.

PloS one - 1 Jan 2014

Zhu Lingyan, Xu Qing, Jiang Ling, Huang He, Li Shuang

Abstract excerpt

Although traditional mutation is still an attractive approach for strain improvement, it is tedious, time-consuming, and inefficient to screen for surfactin producing strains. To overcome this, we developed a high-throughput screening method for surfactin producing mutants by applying polydiacetylene (PDA) vesicles as sensors with visible chromatic change from blue to red, detected as colorimetric response (CR%)...

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Identifiers

PMID: 24498439
DOI: 10.1371/journal.pone.0088207
PMCID: PMC3912180

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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