Article
The Influence of HLA and KIR Genes on Malignant Melanoma Development and Progression.
Archivum immunologiae et therapiae experimentalis - 1 Dec 2016
Kandilarova Snezhina Mihailova, Paschen Annette, Mihaylova Anastassia, Ivanova Milena, Schadendorf Dirk, Naumova Elissaveta
Abstract excerpt
Many studies have described the role of killer immunoglobulin-like receptors (KIRs) and their cognate human leukocyte antigen (HLA) class I ligands in the immune protection against melanoma, but the effect of these markers on intra-individual variations in tumor development and progression has remained less clear. We performed KIR, HLA, and KIR/ligand analysis in 283 patients with malignant melanoma in order to...
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