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Article

Cytogenetic Prognostication Within Medulloblastoma Subgroups

4 Feb 2014

Abstract excerpt

PURPOSE: Medulloblastoma comprises four distinct molecular subgroups: WNT, SHH, Group 3, and Group 4. Current medulloblastoma protocols stratify patients based on clinical features: patient age, metastatic stage, extent of resection, and histologic variant. Stark prognostic and genetic differences among the four subgroups suggest that subgroup-specific molecular biomarkers could improve patient prognostication....

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PMID: 24493713
DOI: 10.1200/jco.2013.50.9539

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