Article
Medulloblastoma molecular dissection: the way toward targeted therapy.
Current opinion in oncology - 1 Nov 2013
Remke Marc, Ramaswamy Vijay, Taylor Michael D
Abstract excerpt
PURPOSE OF REVIEW: The advent of integrated genomics revealed profound insights into medulloblastoma pathogenesis. However, these biological findings have yet to be translated into the clinic, as current treatment comprises surgical resection, conventional irradiation, and chemotherapy resulting in significant long-term sequelae. We sought to highlight the potential areas for targeted therapy based on our new...
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