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Article

17β-Estradiol induces sulfotransferase 2A1 expression through estrogen receptor α.

Drug metabolism and disposition: the biological fate of chemicals - 1 Apr 2014

Li Wei, Ning Miaoran, Koh Kwi Hye, Kim Heesue, Jeong Hyunyoung

Abstract excerpt

Sulfotransferase (SULT) 2A1 catalyzes sulfonation of drugs and endogenous compounds and plays an important role in xenobiotic metabolism as well as in the maintenance of steroid and lipid homeostasis. A recent study showed that 17β-estradiol (E2) increases the mRNA levels of SULT2A1 in human hepatocytes. Here we report the underlying molecular mechanisms. E2 enhanced SULT2A1 expression in human hepatocytes and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24492894
DOI: 10.1124/dmd.113.055178
PMCID: PMC3965899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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