Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effects of aging on the expression of Wnt pathway genes in mouse tissues.

Age (Dordrecht, Netherlands) - 1 Jun 2014

Hofmann Jeffrey W, McBryan Tony, Adams Peter D, Sedivy John M

Abstract excerpt

The Wnt signaling pathway is involved in the regulation of tissue patterning and organ development during embryogenesis and continues to contribute to the maintenance of tissue homeostasis in adulthood. Recently, Wnt signaling has also been implicated in the establishment and progression of replicative cellular senescence. Given the known roles of tissue homeostasis and cellular senescence in aging, we sought to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Cell Survival
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle, Skeletal

Share to Wnt Proteins

Share to Wnt Signaling Pathway

Source

Open in PubMed Open full text

Identifiers

PMID: 24488586
DOI: 10.1007/s11357-014-9618-3
PMCID: PMC4082588

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effects of aging on the expression of Wnt pathway genes in mouse tissues.PMID 24488586Read ↗

AGEMAP: A Gene Expression Database for Aging in MiceSemantic proximity Read ↗

LEF1 isoforms regulate cellular senescence and agingSemantic proximity Read ↗

A genomic perspective of the aging human and mouse lung with a focus on immune response and cellular senescenceSemantic proximity Read ↗

LEF1 isoforms regulate cellular senescence and agingSemantic proximity Read ↗

Conserved aging-related signatures of senescence and inflammation in different tissues and speciesSemantic proximity Read ↗

Remodeling of epigenome and transcriptome landscapes with aging in mice reveals widespread induction of inflammatory responsesSemantic proximity Read ↗

Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and genderSemantic proximity Read ↗

p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and RbSemantic proximity Read ↗

Meta-Profiles of Gene Expression during Aging: Limited Similarities between Mouse and Human and an Unexpectedly Decreased Inflammatory SignatureSemantic proximity Read ↗

Ageing transcriptome meta-analysis reveals similarities and differences between key mammalian tissuesSemantic proximity Read ↗

CircRREB1 mediates lipid metabolism related senescent phenotypes in chondrocytes through FASN post-translational modifications.Semantic proximity Read ↗

Mouse microRNA signatures in joint ageing and post-traumatic osteoarthritisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.