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Article

Greater impact of dietary fat manipulation than apolipoprotein E genotype on ex vivo cytokine production - insights from the SATgenε study.

Cytokine - 1 Apr 2014

Koutsos Athanasios, Jackson Kim G, Lockyer Stacey, Carvalho-Wells Andrew, Minihane Anne M, Lovegrove Julie A

Abstract excerpt

Apolipoprotein E (APOE) genotype is believed to play an important role in cardiovascular risk. APOE4 carriers have been associated with higher blood lipid levels and a more pro-inflammatory state compared with APOE3/E3 individuals. Although dietary fat composition has been considered to modulate the inflammatory state in humans, very little is known about how APOE genotype can impact on this response. In a...

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Identifiers

PMID: 24485322
DOI: 10.1016/j.cyto.2013.12.015
PMCID: PMC3969721

Genes

APOE
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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