Article
Role of single nucleotide polymorphisms of pro-inflammatory cytokine genes in the relationship between serum lipids and inflammatory parameters, and the lipid-lowering effect of fish oil in healthy males.
Clinical nutrition (Edinburgh, Scotland) - 1 Oct 2004
Markovic Olivera, O'Reilly Gillian, Fussell Helen M, Turner Stephen J, Calder Philip C, Howell William M, Grimble Robert F
Abstract excerpt
BACKGROUND AND AIMS: Lipid metabolism, obesity and inflammation are intimately related. Plasma triglycerides increase during the inflammatory response to pathogens and obesity increases inflammatory stress. Pro-inflammatory cytokines are secreted by adipocytes in uninfected obese subjects. Polymorphisms (SNPs) in cytokine genes influence the intensity of cytokine production and inflammatory stress. Fish oil has...
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