Article
Identification and validation of PROM1 and CRTC2 mutations in lung cancer patients.
Molecular cancer - 31 Jan 2014
He Yanqi, Li Yalun, Qiu Zhixin, Zhou Bin, Shi Shaoqin, Zhang Kui, Luo Yangkun, Huang Qian, Li Weimin
Abstract excerpt
BACKGROUND: Genetic alterations could be responsible lung cancer, the leading cause of worldwide cancer death. METHODS: This study investigated gene mutations in a Han Chinese family of lung cancer using the whole genome exome sequencing and subsequent Sanger sequencing validation and then confirmed alteration of prominin 1(PROM1) and cyclic AMP-response element binding protein-regulated transcription...
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