Article
Sequence similarity of Clostridium difficile strains by analysis of conserved genes and genome content is reflected by their ribotype affiliation.
PloS one - 1 Jan 2014
Kurka Hedwig, Ehrenreich Armin, Ludwig Wolfgang, Monot Marc, Rupnik Maja, Barbut Frederic, Indra Alexander, Dupuy Bruno, Liebl Wolfgang
Abstract excerpt
PCR-ribotyping is a broadly used method for the classification of isolates of Clostridium difficile, an emerging intestinal pathogen, causing infections with increased disease severity and incidence in several European and North American countries. We have now carried out clustering analysis with selected genes of numerous C. difficile strains as well as gene content comparisons of their genomes in order to...
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