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Article

Building an Ovary: Insights into Establishment of Somatic Cell Lineages in the Mouse

1 Jan 2014

Abstract excerpt

The molecular pathways that drive the differentiation of somatic cell populations in the testis and ovary have been the subjects of intensive research over the past decade. It is now clear that ovarian differentiation is a coordinate event driven by secreted factors including R-spondin1, WNT4, and follistatin and transcriptional regulators such as β-catenin and FOXL2. These factors direct bipotential somatic cell...

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PMID: 24480990
DOI: 10.1159/000358072

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