Article
Genome Wide Sampling Sequencing for SNP Genotyping: Methods, Challenges and Future Development.
International journal of biological sciences - 1 Jan 2016
Jiang Zhihua, Wang Hongyang, Michal Jennifer J, Zhou Xiang, Liu Bang, Woods Leah C Solberg, Fuchs Rita A
Abstract excerpt
Genetic polymorphisms, particularly single nucleotide polymorphisms (SNPs), have been widely used to advance quantitative, functional and evolutionary genomics. Ideally, all genetic variants among individuals should be discovered when next generation sequencing (NGS) technologies and platforms are used for whole genome sequencing or resequencing. In order to improve the cost-effectiveness of the process, however,...
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