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Multi-Omics Study of Keystone Species in a Cystic Fibrosis Microbiome

7 Nov 2021

Abstract excerpt

Ecological networking and in vitro studies predict that anaerobic, mucus-degrading bacteria are keystone species in cystic fibrosis (CF) microbiomes. The metabolic byproducts from these bacteria facilitate the colonization and growth of CF pathogens like Pseudomonas aeruginosa. Here, a multi-omics study informed the control of putative anaerobic keystone species during a transition in antibiotic therapy of a CF...

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PMID: 34769481
DOI: 10.3390/ijms222112050

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