Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasma concentration of platelet-derived microparticles is related to painful vaso-occlusive phenotype severity in sickle cell anemia.

PloS one - 1 Jan 2014

Nebor Danitza, Bowers Andre, Connes Philippe, Hardy-Dessources Marie-Dominique, Knight-Madden Jennifer, Cumming Vanessa, Reid Marvin, Romana Marc

Abstract excerpt

High plasma level of microparticles (MPs) deriving mainly from erythrocytes and platelets has been detected in sickle cell anemia (SCA) patients. Flow cytometry was used to determine the concentration of MPs in two groups of SCA patients exhibiting marked differences in painful vaso-occlusive crisis rates [a non-severe group (n = 17) and a severe group (n = 12)], and in a control group composed of healthy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anemia, Sickle Cell
Share to Blood Platelets

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell-Derived Microparticles

Share to Erythrocytes

Share to Flow Cytometry

Share to Particle Size

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 24475257
DOI: 10.1371/journal.pone.0087243
PMCID: PMC3901744

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma concentration of platelet-derived microparticles is related to painful vaso-occlusive phenotype severity in sickle cell anemia.PMID 24475257Read ↗

Insight into the complex pathophysiology of sickle cell anaemia and possible treatmentSemantic proximity Read ↗

Influence of Hemoglobin Variants on Vaso-Occlusive Phenomena in Sickle Cell Anemia: A ReviewSemantic proximity Read ↗

The role of blood rheology in sickle cell disease.Semantic proximity Read ↗

Platelet distribution width (PDW) is increased in vaso-occlusive crisis in sickle cell disease.Semantic proximity Read ↗

New insights into the pathophysiology and development of novel therapies for sickle cell diseaseSemantic proximity Read ↗

Kinetics of sickle cell biorheology and implications for painful vasoocclusive crisis.Semantic proximity Read ↗

Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes.Semantic proximity Read ↗

Extracellular microvesicle microRNAs in children with sickle cell anaemia with divergent clinical phenotypes.Semantic proximity Read ↗

Role of Macrophages in Sickle Cell Disease Erythrophagocytosis and ErythropoiesisSemantic proximity Read ↗

Haptoglobin Genotypes Associated with Vaso-Occlusive Crisis in Sickle Cell Anemia Patients of Eastern India.Semantic proximity Read ↗

A novel red blood cell deformability biomarker is associated with hemolysis and vaso-occlusive crises in sickle cell diseaseSemantic proximity Read ↗

Comparison of Phosphatidylserine-Exposing Red Blood Cells, Fragmented Red Blood Cells and Red Blood Cell-Derived Microparticles in β-Thalassemia/HbE PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.