Article
Herpes zoster caused by vaccine-strain varicella zoster virus in an immunocompetent recipient of zoster vaccine.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Apr 2014
Tseng Hung Fu, Schmid D Scott, Harpaz Rafael, LaRussa Philip, Jensen Nancy J, Rivailler Pierre, Radford Kay, Folster Jennifer, Jacobsen Steven J
Abstract excerpt
We report the first laboratory-documented case of herpes zoster caused by the attenuated varicella zoster virus (VZV) contained in Zostavax in a 68-year-old immunocompetent adult with strong evidence of prior wild-type VZV infection. The complete genome sequence of the isolate revealed that the strain carried 15 of 42 (36%) recognized varicella vaccine-associated single-nucleotide polymorphisms, including all 5...
Topics
- Aged
- DNA, Viral
- Female
- Genome, Viral
- Herpes Zoster
- Herpes Zoster Vaccine
- Herpesvirus 3, Human
- Humans
- Molecular Sequence Data
- Polymorphism, Single Nucleotide
