Article
Restriction fragment length polymorphism of polymerase chain reaction products from vaccine and wild-type varicella-zoster virus isolates.
Journal of virology - 1 Feb 1992
LaRussa P, Lungu O, Hardy I, Gershon A, Steinberg S P, Silverstein S
Abstract excerpt
The nucleotide changes that result in two restriction endonuclease polymorphisms that differentiate wild-type varicella-zoster virus (VZV) from the vaccine strain were determined. Oligonucleotide primers that flank these sites were used to amplify the intervening sequences with the polymerase cha...
Topics
- Base Sequence
- Cell Line
- Chickenpox Vaccine
- Cloning, Molecular
- DNA Probes
- DNA, Viral
- Deoxyribonucleases, Type II Site-Specific
- Genetic Variation
- Herpesvirus 3, Human
- Humans
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
