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Dengue virus NS4A cytoplasmic domain binding to liposomes is sensitive to membrane curvature.

Biochimica et biophysica acta - 1 May 2015

Hung Yu-Fu, Schwarten Melanie, Schünke Sven, Thiagarajan-Rosenkranz Pallavi, Hoffmann Silke, Sklan Ella H, Willbold Dieter, Koenig Bernd W

Abstract excerpt

Dengue virus (DENV) infection is a growing public health threat with more than one-third of the world's population at risk. Non-structural protein 4A (NS4A), one of the least characterized viral proteins, is a highly hydrophobic transmembrane protein thought to induce the membrane alterations that harbor the viral replication complex. The NS4A N-terminal (amino acids 1-48), has been proposed to contain an...

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PMID: 25644870
DOI: 10.1016/j.bbamem.2015.01.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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