Smoking modifies the associated increased risk of future cardiovascular disease by genetic variation on chromosome 9p21.

doi:10.1371/journal.pone.0085893

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Article

Smoking modifies the associated increased risk of future cardiovascular disease by genetic variation on chromosome 9p21.

PloS one - 1 Jan 2014

Hamrefors Viktor, Hedblad Bo, Hindy George, Smith J Gustav, Almgren Peter, Engström Gunnar, Sjögren Marketa, Gränsbo Klas, Orho-Melander Marju, Melander Olle

Abstract excerpt

AIMS: Genetic predisposition for cardiovascular disease (CVD) is likely to be modified by environmental exposures. We tested if the associated risk of CVD and CVD-mortality by the single nucleotide polymorphism rs4977574 on chromosome 9p21 is modified by life-style factors. METHODS AND RESULTS: A...

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PMID: 24465769
DOI: 10.1371/journal.pone.0085893
PMCID: PMC3899088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24465769-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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