Article
Iron deficiency alters megakaryopoiesis and platelet phenotype independent of thrombopoietin.
American journal of hematology - 1 May 2014
Evstatiev Rayko, Bukaty Adam, Jimenez Kristine, Kulnigg-Dabsch Stefanie, Surman Lidia, Schmid Werner, Eferl Robert, Lippert Kathrin, Scheiber-Mojdehkar Barbara, Kvasnicka Hans Michael, Khare Vineeta, Gasche Christoph
Abstract excerpt
Iron deficiency is a common cause of reactive thrombocytosis, however, the exact pathways have not been revealed. Here we aimed to study the mechanisms behind iron deficiency-induced thrombocytosis. Within few weeks, iron-depleted diet caused iron deficiency in young Sprague-Dawley rats, as refle...
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