Article
Association of the Cylin D1 G870A polymorphism with laryngeal cancer: are they really related?
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Verim Aysegul, Ozkan Nazli, Turan Saime, Korkmaz Gurbet, Cacina Canan, Yaylim Ilhan, Isbir Turgay
Abstract excerpt
BACKGROUND: Cylin D1(CCDN1) is an important regulator of the cell cycle whose alterations are thought to be involved in cancer development. There have been many studies indicating CCDN1 amplification or over- expression in a variety of cancer types. In addition to gene amplification, the G870A polymorphism may be related with altered CCDN1 activity, and therefore with cancer development. This hypothesis has been...
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