Article
Nuclear HIF1A expression is strongly prognostic in sporadic but not familial male breast cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2014
Deb Siddhartha, Johansson Ida, Byrne David, Nilsson Cecilia, Constable Leonie, Fjällskog Marie-Louise, Dobrovic Alexander, Hedenfalk Ingrid, Fox Stephen B
Abstract excerpt
Male breast cancer is poorly understood with a large proportion arising in the familial context particularly with the BRCA2 germline mutation. As phenotypic and genotypic differences between sporadic and familial male breast cancers have been noted, we investigated the importance of a hypoxic drive in these cancers as this pathway has been shown to be of importance in familial female breast cancer. Expression of...
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