Article
Adrenal cortical neoplasms: a study of clinicopathological features related to epidermal growth factor receptor gene status.
Diagnostic pathology - 23 Jan 2014
Zhang Jing, Wang Cuiping, Gao Jie, Sun Jian, Zeng Xuan, Wu Shafei, Liang Zhiyong
Abstract excerpt
BACKGROUND: Adrenocortical carcinoma (ACC) is a rare but highly malignant neoplasm with limited treatment options. METHODS: In this study, the clinicopathological features of 22 ACCs and 22 adrenocortical adenomas (ACA) were analyzed, and the EGFR protein expression, EGFR gene mutation status and EGFR gene copy number alteration of all tumors were examined using immunohistochemistry, fluorescence in situ...
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