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Update on Biology and Genomics of Adrenocortical Carcinomas: Rationale for Emerging Therapies

13 May 2022

Abstract excerpt

The adrenal glands are paired endocrine organs that produce steroid hormones and catecholamines required for life. Adrenocortical carcinoma (ACC) is a rare and often fatal cancer of the peripheral domain of the gland, the adrenal cortex. Recent research in adrenal development, homeostasis, and disease have refined our understanding of the cellular and molecular programs controlling cortical growth and renewal,...

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PMID: 35551369
DOI: 10.1210/endrev/bnac012

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