Article
Interleukin-20 receptor expression in the trabecular meshwork and its implication in glaucoma.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics - 1 Jan 2000
Keller Kate E, Yang Yong-Feng, Sun Ying Ying, Sykes Renee, Gaudette Natalie Donna, Samples John R, Acott Ted S, Wirtz Mary K
Abstract excerpt
PURPOSE: To determine whether interleukin-20 receptors (IL-20R) are expressed in trabecular meshwork cells and the effect of a T104M mutation in IL-20R2 on downstream cellular functions. METHODS: Evaluation of signal transducer and activator of transcription (STAT)3 phosphorylation and generic matrix metalloproteinase (MMP) activity in primary open angle glaucoma (POAG) dermal fibroblasts (pHDF) with the T104M...
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