Article
Neuropathologic assessment of dementia markers in identical and fraternal twins.
Brain pathology (Zurich, Switzerland) - 1 Jul 2014
Iacono Diego, Volkman Inga, Nennesmo Inger, Pedersen Nancy L, Fratiglioni Laura, Johansson Boo, Karlsson David, Winblad Bengt, Gatz Margaret
Abstract excerpt
Twin studies are an incomparable source of investigation to shed light on genetic and non-genetic components of neurodegenerative diseases, as Alzheimer's disease (AD). Detailed clinicopathologic correlations using twin longitudinal data and post-mortem examinations are mostly missing. We describe clinical and pathologic findings of seven monozygotic (MZ) and dizygotic (DZ) twin pairs. Our findings show good...
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