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Article

Clinicopathological concordance and discordance in three monozygotic twin pairs with familial Alzheimer's disease.

Journal of neurology, neurosurgery, and psychiatry - 1 Oct 2007

Brickell Kiri L, Leverenz James B, Steinbart Ellen J, Rumbaugh Malia, Schellenberg Gerard D, Nochlin David, Lampe Thomas H, Holm Ida E, Van Deerlin Vivianna, Yuan Wuxing, Bird Thomas D

Abstract excerpt

AIM: Neuropathological examination of both individuals in a monozygotic (MZ) twin pair with Alzheimer's disease (AD) is rare, especially in the molecular genetic era. We had the opportunity to assess the concordance and discordance of clinical presentation and neuropathology in three MZ twin pairs with AD. METHODS: The MZ twins were identified and characterised by the University of Washington Alzheimer's Disease...

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Identifiers

PMID: 17615170
DOI: 10.1136/jnnp.2006.113803
PMCID: PMC2117553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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