Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interplay of choline metabolites and genes in patient-derived breast cancer xenografts

21 Jan 2014

Abstract excerpt

INTRODUCTION: Dysregulated choline metabolism is a well-known feature of breast cancer, but the underlying mechanisms are not fully understood. In this study, the metabolomic and transcriptomic characteristics of a large panel of human breast cancer xenograft models were mapped, with focus on choline metabolism. METHODS: Tumor specimens from 34 patient-derived xenograft models were collected and divided in two....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced MRI Techniques and Applications
Share to Folate and B Vitamins Research
Share to Neurological disorders and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24447408
DOI: 10.1186/bcr3597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interplay of choline metabolites and genes in patient-derived breast cancer xenograftsPMID 24447408Read ↗

Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft modelsSemantic proximity Read ↗

Characterization of breast cancers and therapy response by MRS and quantitative gene expression profiling in the choline pathway.Semantic proximity Read ↗

Abnormal Choline Phospholipid Metabolism in Breast and Ovary Cancer:Molecular Bases for Noninvasive Imaging ApproachesSemantic proximity Read ↗

The PD-L1 metabolic interactome intersects with choline metabolism and inflammationSemantic proximity Read ↗

The PD-L1 metabolic interactome intersects with choline metabolism and inflammationSemantic proximity Read ↗

Mapping choline metabolites in normal and transformed cellsSemantic proximity Read ↗

Exploring novel aspects of choline phospholipid metabolism in cancer using metabolomicsSemantic proximity Read ↗

Mechanisms of indomethacin-induced alterations in the choline phospholipid metabolism of breast cancer cells.Semantic proximity Read ↗

Metabolomic Profiling of Blood-Derived Microvesicles in Breast Cancer PatientsSemantic proximity Read ↗

Correlated metabolomic, genomic, and histologic phenotypes in histologically normal breast tissue.Semantic proximity Read ↗

Metabolic phenotyping of human blood plasma: a powerful tool to discriminate between cancer types?Semantic proximity Read ↗

Increased choline kinase activity in human breast carcinomas: clinical evidence for a potential novel antitumor strategySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.