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Article

Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminal-like breast cancer xenograft models

17 Aug 2010

Abstract excerpt

BACKGROUND: Increased concentrations of choline-containing compounds are frequently observed in breast carcinomas, and may serve as biomarkers for both diagnostic and treatment monitoring purposes. However, underlying mechanisms for the abnormal choline metabolism are poorly understood. METHODS: The concentrations of choline-derived metabolites were determined in xenografted primary human breast carcinomas,...

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PMID: 20716336
DOI: 10.1186/1471-2407-10-433

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