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Article

Mechanisms of indomethacin-induced alterations in the choline phospholipid metabolism of breast cancer cells.

Neoplasia (New York, N.Y.) - 1 Sept 2006

Glunde Kristine, Jie Chunfa, Bhujwalla Zaver M

Abstract excerpt

Human mammary epithelial cells (HMECs) exhibit an increase in phosphocholine (PC) and total choline-containing compounds, as well as a switch from high glycerophosphocholine (GPC)/low PC to low GPC/high PC, with progression to malignant phenotype. The treatment of human breast cancer cells with a nonsteroidal anti-inflammatory agent, indomethacin, reverted the high PC/low GPC pattern to a low PC/high GPC pattern...

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Share to Anti-Inflammatory Agents, Non-Steroidal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 16984733
DOI: 10.1593/neo.06187
PMCID: PMC1584299

Genes

CSF2
EDN1
JUNB
RHOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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