Article
The effect of heat shock protein 27 on extravillous trophoblast differentiation and on eukaryotic translation initiation factor 4E expression.
Molecular human reproduction - 1 May 2014
Sadeh-Mestechkin D, Epstein Shochet G, Pomeranz M, Fishman A, Drucker L, Biron-Shental T, Lishner M, Tartakover Matalon S
Abstract excerpt
Heat shock protein (HSP27) is expressed in human placentae. Previously, we showed that HSP27 is expressed in the villous cell column of first trimester placental explants and in extravillous trophoblast (EVT) cells. EVT differentiation is accompanied by increased motility, matrix metalloproteinase (MMP) activity, decreased proliferation and expression of specific markers such as HLAG and CD9. HSP27 regulates cell...
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