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Article

Toll-like receptor 2 participates in the response to lung injury in a murine model of pulmonary contusion.

Shock (Augusta, Ga.) - 1 Oct 2007

Hoth J Jason, Hudson William P, Brownlee Noel A, Yoza Barbara K, Hiltbold Elizabeth M, Meredith J Wayne, McCall Charles E

Abstract excerpt

Blunt chest trauma resulting in pulmonary contusion with an accompanying acute inflammatory response is a common but poorly understood injury. We report that Toll-like receptor (TLR) 2 participates in the inflammatory response to lung injury. To show this, we use a model of pulmonary contusion in the mouse that is similar to that observed clinically in humans based on histologic, morphologic, and biochemical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17558351
DOI: 10.1097/shk.0b013e318048801a

Genes

TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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