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Common Mechanism for RNA Encapsidation by Negative-Strand RNA Viruses

16 Jan 2014

Abstract excerpt

UNLABELLED: The nucleocapsid of a negative-strand RNA virus is assembled with a single nucleocapsid protein and the viral genomic RNA. The nucleocapsid protein polymerizes along the length of the single-strand genomic RNA (viral RNA) or its cRNA. This process of encapsidation occurs concomitantly with genomic replication. Structural comparisons of several nucleocapsid-like particles show that the mechanism of RNA...

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PMID: 24429372
DOI: 10.1128/jvi.03483-13

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