Article
The presence of EGFR mutations predicts the response in Chinese non-small cell lung cancer patients treated with erlotinib.
The International journal of biological markers - 25 Jun 2014
Li Rui-Chao, Zheng Li-Jun, Fang Ming-Hao, Yu Shi-Ying
Abstract excerpt
Non-small cell lung cancer (NSCLC) is a leading cause of death worldwide. The upregulation of the epidermal growth factor receptor (EGFR) due to mutations has been observed in a number of cancers, and tyrosine kinase inhibitors (TKIs), such as gefitinib and erlotinib, which specifically target EGFR signaling, have been used to treat NSCLC patients. The presence of EGFR mutations was previously shown to confer...
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