Article
Clinical significance of epidermal growth factor receptor gene mutations on treatment outcome after first-line cytotoxic chemotherapy in Japanese patients with non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jul 2007
Hotta Katsuyuki, Kiura Katsuyuki, Toyooka Shinichi, Takigawa Nagio, Soh Junichi, Fujiwara Yoshiro, Tabata Masahiro, Date Hiroshi, Tanimoto Mitsune
Abstract excerpt
INTRODUCTION: The relationship between the EGFR gene mutation status and clinical outcome has not fully been assessed in patients with non-small cell lung cancer (NSCLC) who received cytotoxic agents. The aim of this study was to clarify its association. We also examined whether this association could be affected by previous gefitinib treatment. METHODS: Patients with advanced or postoperative recurrent NSCLC who...
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