Article
Impaired GABAB receptor signaling dramatically up-regulates Kiss1 expression selectively in nonhypothalamic brain regions of adult but not prepubertal mice.
Endocrinology - 1 Mar 2014
Di Giorgio Noelia P, Semaan Sheila J, Kim Joshua, López Paula V, Bettler Bernhard, Libertun Carlos, Lux-Lantos Victoria A, Kauffman Alexander S
Abstract excerpt
Kisspeptin, encoded by Kiss1, stimulates reproduction and is synthesized in the hypothalamic anteroventral periventricular and arcuate nuclei. Kiss1 is also expressed at lower levels in the medial amygdala (MeA) and bed nucleus of the stria terminalis (BNST), but the regulation and function of Kiss1 there is poorly understood. γ-Aminobutyric acid (GABA) also regulates reproduction, and female GABAB1 receptor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
