Article
Bosutinib: a review of its use in patients with Philadelphia chromosome-positive chronic myelogenous leukemia.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy - 1 Feb 2014
Syed Yahiya Y, McCormack Paul L, Plosker Greg L
Abstract excerpt
Bosutinib (Bosulif®) is an orally administered small molecule tyrosine kinase inhibitor (TKI) of BCR-ABL and SRC family kinases. It is indicated for the treatment of adult patients with chronic-, accelerated-, or blast-phase Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) with resistance or intolerance to prior therapy (imatinib, dasatinib, or nilotinib) [USA] or for a small...
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