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Article

New in vitro phenotypic assay for epilepsy: fluorescent measurement of synchronized neuronal calcium oscillations.

PloS one - 1 Jan 2014

Pacico Nathalie, Mingorance-Le Meur Ana

Abstract excerpt

Research in the epilepsy field is moving from a primary focus on controlling seizures to addressing disease pathophysiology. This requires the adoption of resource- and time-consuming animal models of chronic epilepsy which are no longer able to sustain the testing of even moderate numbers of compounds. Therefore, new in vitro functional assays of epilepsy are needed that are able to provide a medium throughput...

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Identifiers

PMID: 24416277
DOI: 10.1371/journal.pone.0084755
PMCID: PMC3885603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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